- Title
- Management of metastatic thyroid cancer in pregnancy: risk and uncertainty
- Creator
- Rowe, Christopher W.; Murray, Kirsten; Woods, Andrew; Gupta, Sandeep; Smith, Roger; Wynne, Katie
- Relation
- Endocrinology, Diabetes & Metabolism Case Reports Vol. 2016, Issue 1, no. 16-0071
- Publisher Link
- http://dx.doi.org/10.1530/EDM-16-0071
- Publisher
- BioScientifica
- Resource Type
- journal article
- Date
- 2016
- Description
- Metastatic thyroid cancer is an uncommon condition to be present at the time of pregnancy, but presents a challenging paradigm of care. Clinicians must balance the competing interests of long-term maternal health, best achieved by iatrogenic hyperthyroidism, regular radioiodine therapy and avoidance of dietary iodine, against the priority to care for the developing foetus, with inevitable compromise. Additionally, epidemiological and cellular data support the role of oestrogen as a growth factor for benign and malignant thyrocytes, although communicating the magnitude of this risk to patients and caregivers, as well as the uncertain impact of any pregnancy on long-term prognosis, remains challenging. Evidence to support treatment decisions in this uncommon situation is presented in the context of a case of a pregnant teenager with known metastatic papillary thyroid cancer and recent radioiodine therapy.
- Subject
- adolescent/young adult; thyroid cancer; pregnancy; papillary thyroid cancer; lung function testing; premature labour; exercise tolerance; iron supplements
- Identifier
- http://hdl.handle.net/1959.13/1416659
- Identifier
- uon:37092
- Identifier
- ISSN:2052-0573
- Rights
- This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.
- Language
- eng
- Full Text
- Reviewed
- Hits: 4542
- Visitors: 4784
- Downloads: 260
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | ATTACHMENT02 | Publisher version (open access) | 694 KB | Adobe Acrobat PDF | View Details Download |